NSK-SD and More Benefits

Blood Flow Improving Effect

We have a human study that shows a single dose of NSK-SD is effective in increasing blood flow to hands and feet.

  • Luchi et al. 2006 - 15 healthy men and women were given a single dose of 2,000FU of NSK-SD. Increased blood flow was observed in the fingers and back of hands compared to baseline, 80, 120, and 180 minutes after consumption.

 

Above are the results of one subject 180min after intake of NSK-SD vs. Placebo.

 

  • Nara et al. 2023 - 9 healthy subjects were given a single dose of nattokinase or a placebo before immersing their hands in cold water. The nattokinase group showed significantly quicker recovery times in skin temperature after the water immersion than the placebo group in this double-blind, placebo-controlled, crossover study (p < 0.05). The results supported the findings that nattokinase improves blood flow through its effects on skin temperature, which is predominately controlled by skin surface blood flow.

 

Anti-Inflammatory Effect

We have a human study that shows a single dose of NSK-SD is effective in decreasing inflammation in subjects with high CRP levels.

  • Jeske et al. 2011 - 10 subjects that each had three or more cardiovascular risk factors present were given a single dose of 2,000FU of NSK-SD and the CRP levels in the blood were measured over 24 hours following intake. Mean CRP levels decreased progressively for 12 hours post-dose. The greatest effect was observed in patients with higher CRP levels pre-treatment. The highest CRP value dropped by 72%.

Why do we care about CRP levels?

Elevation in CRP levels have been associated with the following:

  • Cardiovascular Disease

  • Atherosclerosis

  • Heart Disease Risk

  • Systemic Inflammation

  • Metabolic Syndrome

  • Trauma, Cancer, Infection, etc.

In 2003 AHA and CDC published a joint scientific statement recommending the measurement of CRP for clinical and public health assessment of coronary heart disease and stroke.