Published Study Shows Nattokinase Accelerates Skin Temperature Recovery

A recent study discovered that nattokinase can accelerate skin temperature recovery after cold water immersion. Skin temperature is largely controlled by skin surface blood flow, and the findings further substantiate the results of a previous study that showed nattokinase improves blood flow.

Nattokinase has already been backed by numerous studies for its heart health benefits. These study results include the prevention and degradation of blood clots, reduction in high blood pressure, improvement of clumping platelets and red blood cells, improvement in blood flow, and more.

In this most recent double-blind, placebo-controlled, crossover intervention study, 9 male subjects were given a single dose of nattokinase or a placebo and then immersed their hands in a cold water bath for 1 minute. Skin temperature was then measured in intervals after immersion. The findings showed that the skin temperatures of the middle finger, palm, and back of the right hand recovered more quickly by nattokinase intake than by placebo intake (p < 0.05). It was also noted that nattokinase did not disturb the body’s normal circulatory response or sympathetic nervous system. 

The results may especially pose the benefit of nattokinase for individuals more sensitive to the cold, such as women and the elderly, through its potential to prevent excessive vasoconstriction.

The mentioned study was published in CellPress on July 6, 2023 under the title, “A single dose of oral nattokinase accelerates skin temperature recovery after cold water immersion: A double-blind, placebo-controlled crossover study.”

Nattokinase is a natural enzyme that is derived from a fermented soybean dish called natto, which is regularly enjoyed as a breakfast meal in Japan. Natto has for centuries been known for its heart health benefits and a prospective study showed that Japanese individuals who consumed more natto on a regular basis than those who did not, were associated with significantly decreased risk of mortality due to cardiovascular disease. 

NSK-SD® is the world’s first nattokinase to enter the market and is the only nattokinase that has its own published safety, identity, and efficacy data. NSK-SD® is manufactured by Japan Bio Science Laboratory, who are the pioneers in natto-derived health ingredients including nattokinase, Vitamin K2-MK7 and Bacillus Subtilis Natto. For more information, contact JBSL-USA at (925) 938-2732 or sales@jbsl-net.com and visit www.nsk-sd.info.